I very much want to run a VotA tournament after S4 changes go through (after the publicity run) and we have a steady stream of additional players. That said, and maybe it's premature for this poll, but I'll throw it out there anyway.
Man, that's hard to say. I wouldn't want more than a 3v3, but even that is shaky. I think we'd have more diverse competition if we have a 2v2 bracket. That way it will be split up a little better.
I guess lag has kicked me too hard in the nuts when I've played games that big. I have no doubt that it could be an incredible game but there would need to be a lot more practice with your chosen team to properly time buffs/debuffs, skills/abilities, etc